YK-11
YK11 SARM for sale | High-Purity Research Chemicals | UK Supply
YK11 is a synthetic, steroidal selective androgen receptor modulator (SARM) investigated in vitro for its unique mechanisms, including partial androgen receptor agonism and potential myostatin inhibition via follistatin pathways. Explore our range for your specific research needs.
All listed products are available for direct shipment within the United Kingdom.
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Why Choose Our YK11 Research Chemicals?
Uncompromising Quality Standards
Our YK11 compounds are sourced with a commitment to the highest quality standards essential for precision research applications. We understand that experimental outcomes depend on consistent, reliable chemical inputs.
Comprehensive Purity Verification
Every batch undergoes rigorous analytical testing via HPLC to confirm both identity and purity. We maintain strict quality control procedures to ensure our products meet or exceed their specified purity levels. Each individual product page provides access to batch-specific Certificates of Analysis (CoA), allowing researchers to review detailed analytical data before purchase.
Reliable UK Supply Chain
We maintain consistent stock levels of YK11 research chemicals to support ongoing research protocols without interruption. Our UK-based operations ensure prompt delivery throughout the United Kingdom, minimizing delays to your laboratory work.
Dedicated Technical Support
Our team includes qualified individuals able to address technical inquiries related to product specifications, handling requirements, and storage recommendations for research applications. We provide responsive support to ensure you can make informed decisions about the most appropriate products for your specific research needs.
Understanding YK11 SARM: Scientific Overview
Chemical Profile
YK11 (CAS: 1370003-76-1) is classified as a synthetic, steroidal selective androgen receptor modulator. Its chemical structure, (17α,20E)-17,20-[(1-Methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester, features a steroidal backbone with specific modifications that contribute to its unique pharmacological profile in preclinical investigations.
Mechanism of Action (Reported in Research)
Laboratory research has identified several mechanisms of interest:
Androgen Receptor Interaction: Studies by Kanno et al. (2011) demonstrated that YK11 functions as a partial agonist at the androgen receptor. Unlike full agonists, YK11 does not induce the complete N/C interaction of the AR typically observed with endogenous androgens, suggesting a selective activity profile in cellular models.
Myogenic Pathway Effects: Research using C2C12 myoblast cultures has shown that YK11 influences the expression of follistatin, a protein that acts as an antagonist to myostatin—a negative regulator of muscle development. This follistatin-mediated pathway represents a mechanistically distinct feature compared to other compounds in its class (Kanno et al., 2013).
Osteoblast Activity: Preliminary findings using MC3T3-E1 osteoblast cells suggest potential modulation of markers associated with bone formation processes, though further research is needed to fully characterize these effects.
Areas of Research Interest
YK11 continues to be investigated in preclinical models across several research domains, including:
- Molecular mechanisms of selective androgen receptor modulation
- Regulation of myostatin/follistatin expression pathways
- Signaling cascades in myogenic differentiation
- Structure-activity relationships in steroidal SARMs
- Comparative analysis with non-steroidal SARMs
Our Commitment to Quality & Researcher Safety
We are dedicated to supporting the scientific community with high-quality, accurately identified compounds for legitimate research purposes. All products are supplied with comprehensive safety documentation and handling guidelines to promote safe laboratory practices.
Each product page provides access to:
- Batch-specific Certificate of Analysis
- Safety Data Sheet (SDS)
- Recommended storage conditions
- Solubility information
- Handling precautions
Important Reminder: All products in this category are strictly for research use by qualified individuals only. They are not intended for human or veterinary use under any circumstances.
UK Shipping & Customer Support
Fast, Reliable UK Delivery
We offer several shipping options to meet your research timeline requirements:
* Royal Mail Special Delivery: Next working day by 1pm
* Royal Mail Signed For: 2-3 working days
All orders placed before 3pm Monday-Friday are typically dispatched the same day. Orders are shipped in discreet, appropriate packaging with no indication of contents.
Dedicated Customer Support
Our team is available to assist with inquiries regarding orders, shipping, or product specifications for research applications:
* Email: [email protected]
* Hours: Monday-Friday, 9am-5pm GMT
* Live Chat on Website: 24/7