S-23

S-23 is a selective androgen receptor modulator (SARM) that binds strongly to androgen receptors in muscle and bone tissue. This selective binding drives lean muscle growth and fat loss while sparing some of the off-target effects seen with anabolic steroids. It is one of the more potent SARMs on the market, which is why it is popular for body recomposition.

As a guide and not medical advice, users commonly run S-23 at 10 to 15mg per day for around 8 weeks, taken with food to ease stomach discomfort. Because each capsule is 15mg, staying within that range usually means one capsule a day rather than stacking multiple doses. S-23 is considered too strong for a first ever SARM cycle, so newer users often look at something milder like ostarine first.

Yes, S-23 causes significant suppression of natural testosterone production, so post-cycle therapy is treated as essential rather than optional. A typical approach is clomid at 50mg a day for 4 weeks, or nolvadex at 40mg a day for 2 weeks stepping down to 20mg for another 2 weeks, starting about 24 hours after the last dose. Some users also run testosterone support alongside S-23 itself to offset the suppression during the cycle, with an aromatase inhibitor like anastrozole added if oestrogen-related sides appear.

Reported effects include a drop in HDL cholesterol, some elevation in liver enzymes, and androgenic issues such as acne or hair thinning in those predisposed to it, alongside the testosterone suppression already mentioned. Baseline bloodwork covering testosterone, oestradiol, lipids and liver function before starting, with a repeat around week 4 and again after the cycle, is the sensible way to track how your body is responding. None of this is a substitute for advice from a qualified healthcare professional.

S-23 sits at the stronger end of the SARM spectrum, delivering more noticeable muscle and strength gains than a mild compound like ostarine, but with a heavier suppression and side effect profile to match. It is sometimes paired with cardarine (GW-501516), a PPAR-delta agonist rather than a SARM, which supports fat loss and endurance without adding extra androgen load and can help offset some of the lipid changes S-23 causes. This makes S-23 more suited to experienced users chasing a stronger recomposition effect rather than a first cycle.

Every box of S-23 we stock is authentic iMuscle SARMs product with its own verification check-code, so you can confirm it is legitimate on arrival. Orders placed before midday on a working day go out same-day from our UK warehouse via Royal Mail Tracked 24, with most customers seeing delivery within 1 to 2 working days, all packed in plain, discreet packaging.